Sex‐ and Age‐Specific Metabolic Outcomes of Prolactin Normalisation in Hyperprolactinaemia

PRL normalisation with cabergoline was associated with modest improvements in conventional lipid fractions and a more consistent reduction in the TyG index, suggesting a preferential impact on insulin-resistance-related pathways. The absence of independent effects of sex, age, PRL dynamics, or cabergoline exposure on lipid changes underscores the need for cautious interpretation of statistically significant but small absolute shifts.

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Publication Details

Journal
Clinical Endocrinology
Published
2026-01-14
DOI
https://doi.org/10.1111/cen.70095
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Sex‐ and Age‐Specific Metabolic Outcomes of Prolactin Normalisation in Hyperprolactinaemia

Rocío Villar‐Taibo, Patricia Pérez Castro, FERNANDO CORDIDO, Aida Orois et al.
Clinical Endocrinology
Pituitary Gland Disorders and Treatments
article

Sex‐ and Age‐Specific Metabolic Outcomes of Prolactin Normalisation in Hyperprolactinaemia

Rocío Villar‐Taibo, Patricia Pérez Castro, FERNANDO CORDIDO, Aida Orois, Andreu Simó‐servat, Laura González Fernández, Soralla Civantos, Juan J. Díez, Betina Biagetti, Felicia A. Hanzu, G. Rivero, María Dolores Moure Rodríguez, Miguel Paja, Pedro Iglesias, Victoria Alcázar Lázaro, Cristina Lamas, Eva Fernández‐Rodríguez, Fernando Guerrero‐Pérez, Isabel Pavón de Paz, Carmen María Fernandez de Araoz, Sara de Miranda Lemos Donato, Marta Araujo‐Castro, Noel Roig‐Marín, Elena Outeiriño‐Blanco
article en

Abstract

PRL normalisation with cabergoline was associated with modest improvements in conventional lipid fractions and a more consistent reduction in the TyG index, suggesting a preferential impact on insulin-resistance-related pathways. The absence of independent effects of sex, age, PRL dynamics, or cabergoline exposure on lipid changes underscores the need for cautious interpretation of statistically significant but small absolute shifts.

Clinical Endocrinology
Universidade da Coruña (ES), Universitat Autònoma de Barcelona (ES), Bellvitge University Hospital (ES), University Hospital Complex Of Vigo (ES), Hospital General Universitario Gregorio Marañón (ES), Hospital de Basurto (ES), Complejo Hospitalario Universitario de Santiago (ES), Hospital Universitario de Getafe (ES), Hospital Universitario Puerta de Hierro Majadahonda (ES), Hospital Clínic de Barcelona (ES), Mútua Terrassa (ES), Hospital de Cruces (ES), Complexo Hospitalario Universitario A Coruña (ES), Hospital Universitario de Fuenlabrada (ES), Hospital Universitario Son Espases (ES), Complejo Hospitalario Universitario de Albacete (ES), Hospital Universitario Severo Ochoa (ES), Hospital Universitario Ramón y Cajal (ES), Complejo Hospitalario de Ourense (ES), Universitat de Barcelona (ES)
Gender equality
Openalex Percentile: Top 87%
Pituitary Gland Disorders and Treatments
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