Elevated tRNA halves in olfactory epithelial cells of patients with schizophrenia
Schizophrenia patients' olfactory epithelial cells contain abundant immune-activating tRNA fragments, linking small RNA biology to inflammation and suggesting avenues for diagnostics.
Authors
- Yohei Kirino (ORCID: https://orcid.org/0000-0001-5232-4742)
- Megumi Shigematsu (ORCID: https://orcid.org/0000-0003-3265-5557)
- Chang-Gyu Hahn
- Justin T. Gumas
Institutions
- Thomas Jefferson University (US)
- Computational Physics (United States) (US)
Publication Details
- Journal
- Journal of Clinical Investigation
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1172/jci195148
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Thomas Jefferson University