Epidemiological analysis of human papillomavirus and its subtype infections in 36,248 women in Wuhan, China

The HPV prevalence rate among women in Wuhan was higher than that in certain developed cities in China. Among the three existing vaccines, the nine-valent vaccine is more suitable for women in Wuhan. It is necessary to further promote the cervical cancer vaccination program among young women. In addition, cervical cancer screening should be strongly advocated in perimenopausal women. The high frequency of high-risk HPV subtypes that are not covered by existing vaccines highlights the urgent need for new vaccine development based on the HPV epidemiology in the local population.