Comparison of functional outcomes between tenecteplase and alteplase as bridging thrombolysis prior to mechanical throm-bectomy for acute ischemic stroke patients with large vessel occlusion

In AIS patients with large vessel occlusion undergoing bridging thrombolysis before mechanical thrombectomy, tenecteplase and alteplase showed comparable 3-month functional and safety outcomes.

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Publication Details

Journal
Journal of Zhejiang University (Medical Sciences)
Published
2026-01-15
DOI
https://doi.org/10.3724/zdxbyxb-2025-0639
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparison of functional outcomes between tenecteplase and alteplase as bridging thrombolysis prior to mechanical throm-bectomy for acute ischemic stroke patients with large vessel occlusion

Gongchun Huang, Min Lou, Yaojie Cai, Jianhua CHENG et al.
Journal of Zhejiang University (Medical Sciences)
Acute Ischemic Stroke Management
article

Comparison of functional outcomes between tenecteplase and alteplase as bridging thrombolysis prior to mechanical throm-bectomy for acute ischemic stroke patients with large vessel occlusion

Gongchun Huang, Min Lou, Yaojie Cai, Jianhua CHENG, Yi ZHU, Hui ZHU, Jiansheng YANG, Zhenchan LU
article en

Abstract

In AIS patients with large vessel occlusion undergoing bridging thrombolysis before mechanical thrombectomy, tenecteplase and alteplase showed comparable 3-month functional and safety outcomes.

Journal of Zhejiang University (Medical Sciences)Vol. 55(2)
Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN), Huzhou Central Hospital (CN), Ningbo Medical Center Lihuili Hospital (CN), The People's Hospital of LinXia (CN), First Hospital of Jiaxing (CN), Second Affiliated Hospital of Zhejiang University (CN), Shaoxing People's Hospital (CN)
Zhejiang Medical Association
Openalex Percentile: Top 87%
Acute Ischemic Stroke Management
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