Inhibitory Effect of Ethyl acetate Fraction of Taxus cuspidata S. et Z. on the Lipofuscin Accumulation in Caenorhabditis elegans

Lipofuscin is known as an aging pigment observed when aging proceeds in organic organisms. The intestinal lipofuscin value of Caenorhabditis elegans decreased in the experimental group treated with the ethyl acetate fraction of interest compared to the control group. Among several factors related to aging, movement, body length, and exercise of the pharynx were measured to determine the effect of treatment with the Taxus cuspidata S. et Z. ethyl acetate fraction on nematode intake or growth and motility, respectively. The increase in food intake or body length showed no significant change compared to the control group, but the exercise amount showed a significant increase compared to the control group.