Comparative renal safety of teicoplanin versus vancomycin in older patients: a propensity-matched multicenter study
Teicoplanin demonstrated superior renal safety compared to vancomycin in older patients. The C<sub>min,ss</sub> <40 mg/L was associated with a manageable risk of nephrotoxicity, whereas exposure duration and baseline creatinine could serve as critical parameters for clinical decision-making.
Authors
- T. Liu
- Zhimei Duan (ORCID: https://orcid.org/0000-0002-6076-5406)
- Tao Wang (ORCID: https://orcid.org/0000-0002-7275-3293)
- Lixin Xie
- Y. H. Zhou
- Yaping Yuan (ORCID: https://orcid.org/0009-0004-8737-1396)
- Xiangqun Fang
- Jionghe Wu
- Peng Na
- Hongxia Li
- Xia Wu
- Jing Zhao
Institutions
- Chinese PLA General Hospital (CN)
- PLA Academy of Military Science (CN)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1016/j.ijid.2026.108399
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- General Hospital of People’s Liberation Army