Stressful Life Events in the Year Prior to Diagnosis and Associations With Rheumatoid Arthritis Characteristics at Presentation and One Year Later

Fifty-two percent of patients with newly diagnosed RA reported stressful life events in the year prior to diagnosis that were associated with worse disability, depression, pain, fatigue, sleep, and well-being, but not SDAI, at diagnosis. Poorer patient-reported outcomes persisted at 1 year despite similar improvements in SDAI. Results highlight the potential independent contributions of environmental and psychological factors in the onset and course of RA.

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Publication Details

Journal
The Journal of Rheumatology
Published
2026-01-15
DOI
https://doi.org/10.3899/jrheum.2025-0873
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
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article

Stressful Life Events in the Year Prior to Diagnosis and Associations With Rheumatoid Arthritis Characteristics at Presentation and One Year Later

Carol Hitchon, Glen Hazlewood, Paige Pope, Orit Schieir et al.
The Journal of Rheumatology
Rheumatoid Arthritis Research and Therapies
article

Stressful Life Events in the Year Prior to Diagnosis and Associations With Rheumatoid Arthritis Characteristics at Presentation and One Year Later

Carol Hitchon, Glen Hazlewood, Paige Pope, Orit Schieir, Nicole J. Andersen, G. Boire, Marie‐France Valois, Carter Thorne, Susan J. Bartlett, Bindee Kuriya, Diane Tin, Hugues Allard-Chamard, Vivian P. Bykerk
article en

Abstract

Fifty-two percent of patients with newly diagnosed RA reported stressful life events in the year prior to diagnosis that were associated with worse disability, depression, pain, fatigue, sleep, and well-being, but not SDAI, at diagnosis. Poorer patient-reported outcomes persisted at 1 year despite similar improvements in SDAI. Results highlight the potential independent contributions of environmental and psychological factors in the onset and course of RA.

The Journal of Rheumatology
Western University (CA), Hospital for Special Surgery (US), Université de Sherbrooke (CA), University of Calgary (CA), University of Toronto (CA), Research Manitoba (CA), Arthritis Research Centre of Canada (CA), Université Laval (CA), University of Manitoba (CA), McGill University (CA)
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Openalex Percentile: Top 88%
Rheumatoid Arthritis Research and Therapies
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