Effect of prior traumatic brain injury on Alzheimer’s disease blood biomarkers in Vietnam Veterans

TBI history and severity is a modifier of AD blood test accuracy in prediction of brain amyloid-PET positivity.AD blood tests should be interpreted with caution in Veterans and civilians with TBI history.

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Publication Details

Journal
medRxiv
Published
2026-01-15
DOI
https://doi.org/10.64898/2026.01.13.26344009
Primary Topic
Traumatic Brain Injury Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Effect of prior traumatic brain injury on Alzheimer’s disease blood biomarkers in Vietnam Veterans

Ithamar Ganmore, Orit Segev, Magdalena Brylska, Daniel L. Schwartz et al.
medRxiv
Traumatic Brain Injury Research
article

Effect of prior traumatic brain injury on Alzheimer’s disease blood biomarkers in Vietnam Veterans

Ithamar Ganmore, Orit Segev, Magdalena Brylska, Daniel L. Schwartz, Abigail Livny, Ganna Blazhenets, Edward B. Lee, Agathe Vrillon, Yael Rosen-Lang, Raquel C Gardner, Shlomit Pasternak, Ramit Ravona-Springer, Gil D. Rabinovici, Kristine Yaffe, Lisa Silbert, Susan M. Landau, Nathan Hantke, David Soleimani-Meigooni, Michael W. Weiner, Renaud La Joie
article en

Abstract

TBI history and severity is a modifier of AD blood test accuracy in prediction of brain amyloid-PET positivity.AD blood tests should be interpreted with caution in Veterans and civilians with TBI history.

medRxiv
Tel Aviv University (IL), Oregon Health & Science University (US), University of California, San Francisco (US), University of Washington (US), Sheba Medical Center (IL), University of California System (US), University Memory and Aging Center (US), VA Portland Health Care System (US), Advanced Imaging Research (United States) (US), University of Pennsylvania (US), University of California, Berkeley (US)
U.S. Department of Defense, Alzheimer's Disease Neuroimaging Initiative, National Institutes of Health, National Institute on Aging, Congressionally Directed Medical Research Programs
Good health and well-being
Openalex Percentile: Top 87%
Traumatic Brain Injury Research
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