Air Pollution and Cardiac Remodeling and Function in Patients With Breast Cancer

In this cohort study, PM2.5 and O3 exposure was independently associated with worse cardiac remodeling and function in patients with breast cancer treated with cardiotoxic therapy. These findings highlight the importance of modifying environmental exposures to mitigate cardiovascular disease risk.

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Publication Details

Journal
JAMA Network Open
Published
2026-01-15
DOI
https://doi.org/10.1001/jamanetworkopen.2025.52323
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
0.00
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article

Air Pollution and Cardiac Remodeling and Function in Patients With Breast Cancer

C D Xia, Yehoda M. Martei, Virginia Englefield, B. Ky et al.
JAMA Network Open
Air Quality and Health Impacts
article

Air Pollution and Cardiac Remodeling and Function in Patients With Breast Cancer

C D Xia, Yehoda M. Martei, Virginia Englefield, B. Ky, Hari K. Narayan, Amanda M. Smith, Amy S. Clark, Bénédicte Lefebvre, Anran Huang, Kelly Getz, Kasey J. Leger, Wonyoung Jung, Vivek Narayan, Omotayo Fasan, Daniel Koropeckyj-Cox, Alexander Hutsell, Amber Daniels, Kyunga Ko, Kellie McDermott, Clyde W. Yancy, Tiffany M. Powell-Wiley, Julian D. Marshall
article en

Abstract

In this cohort study, PM2.5 and O3 exposure was independently associated with worse cardiac remodeling and function in patients with breast cancer treated with cardiotoxic therapy. These findings highlight the importance of modifying environmental exposures to mitigate cardiovascular disease risk.

JAMA Network OpenVol. 9(1)
Northwestern University (US), Seattle Children's Hospital (US), National Institutes of Health (US), University of Washington (US), Hospital of the University of Pennsylvania (US), University of California San Diego (US), National Heart, Lung, and Blood Institute (US), National Institute on Minority Health and Health Disparities (US), Seattle University (US), University of Pennsylvania (US)
Good health and well-being
Openalex Percentile: Top 88%
Air Quality and Health Impacts
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