Air Pollution and Cardiac Remodeling and Function in Patients With Breast Cancer
In this cohort study, PM2.5 and O3 exposure was independently associated with worse cardiac remodeling and function in patients with breast cancer treated with cardiotoxic therapy. These findings highlight the importance of modifying environmental exposures to mitigate cardiovascular disease risk.
Authors
- C D Xia (ORCID: https://orcid.org/0000-0003-0418-0371)
- Yehoda M. Martei (ORCID: https://orcid.org/0000-0002-5631-1567)
- Virginia Englefield
- B. Ky
- Hari K. Narayan (ORCID: https://orcid.org/0000-0001-5180-2204)
- Amanda M. Smith (ORCID: https://orcid.org/0000-0002-9881-236X)
- Amy S. Clark (ORCID: https://orcid.org/0000-0002-3685-6535)
- Bénédicte Lefebvre (ORCID: https://orcid.org/0000-0002-8587-7279)
- Anran Huang (ORCID: https://orcid.org/0000-0003-1435-1576)
- Kelly Getz (ORCID: https://orcid.org/0000-0003-2020-5153)
- Kasey J. Leger (ORCID: https://orcid.org/0000-0002-7905-6714)
- Wonyoung Jung (ORCID: https://orcid.org/0000-0003-4749-4637)
- Vivek Narayan (ORCID: https://orcid.org/0000-0001-5150-7432)
- Omotayo Fasan (ORCID: https://orcid.org/0000-0002-8063-5561)
- Daniel Koropeckyj-Cox (ORCID: https://orcid.org/0009-0009-6446-3868)
- Alexander Hutsell
- Amber Daniels
- Kyunga Ko (ORCID: https://orcid.org/0000-0001-8582-2633)
- Kellie McDermott
- Clyde W. Yancy
- Tiffany M. Powell-Wiley
- Julian D. Marshall
Institutions
- Northwestern University (US)
- Seattle Children's Hospital (US)
- National Institutes of Health (US)
- University of Washington (US)
- Hospital of the University of Pennsylvania (US)
- University of California San Diego (US)
- National Heart, Lung, and Blood Institute (US)
- National Institute on Minority Health and Health Disparities (US)
- Seattle University (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.52323
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00