Sex-Dimorphic Associations of Prior Tuberculosis with Hypertension and Inflammatory Signature in People with HIV: a pilot study

A history of TB is associated with hypertension in PWH, particularly among females, and is linked to sex-specific differences in residual inflammatory pathways. These findings suggest that prior TB may contribute to cardiovascular risk in a sex-disparate manner, warranting further investigation.

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Publication Details

Journal
medRxiv
Published
2026-01-15
DOI
https://doi.org/10.64898/2026.01.12.26343987
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Sex-Dimorphic Associations of Prior Tuberculosis with Hypertension and Inflammatory Signature in People with HIV: a pilot study

Sepiso K. Masenga, Frederick Sibbenga, Joreen P. Povia, Chintu Choolwe Simweene
medRxiv
HIV-related health complications and treatments
article

Sex-Dimorphic Associations of Prior Tuberculosis with Hypertension and Inflammatory Signature in People with HIV: a pilot study

Sepiso K. Masenga, Frederick Sibbenga, Joreen P. Povia, Chintu Choolwe Simweene
article en

Abstract

A history of TB is associated with hypertension in PWH, particularly among females, and is linked to sex-specific differences in residual inflammatory pathways. These findings suggest that prior TB may contribute to cardiovascular risk in a sex-disparate manner, warranting further investigation.

medRxiv
Livingstone College (US), Livingstone Hospital (ZA), Mulungushi University (ZM)
American Heart Association, National Institutes of Health, Fogarty International Center, National Institute of Diabetes and Digestive and Kidney Diseases
Good health and well-being
Openalex Percentile: Top 89%
HIV-related health complications and treatments
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