Gestational PBDE concentrations and functional connectivity in adolescents: The HOME Study
Higher gestational PBDE serum concentrations were associated with diminished connectivity in the primary visual cortex. Connectivity patterns also mediated the relationship between gestational ∑<sub>5</sub>BDE concentrations and neurobehavioral outcomes at age 12. These findings suggest that gestational PBDE exposure alters how the brain processes visual information across global networks.
Authors
- Jeffrey Robert Strawn (ORCID: https://orcid.org/0000-0002-7526-2641)
- Jonathan A. Dudley (ORCID: https://orcid.org/0000-0002-5189-9568)
- Andreas Sjödin (ORCID: https://orcid.org/0000-0001-5350-4219)
- Bruce P. Lanphear (ORCID: https://orcid.org/0000-0003-2598-5574)
- Yingying Xu (ORCID: https://orcid.org/0000-0001-5247-3721)
- Kim Cecil
- Alex D. Edmondson
- Aimin Chen
- Joseph M. Braun
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Centers for Disease Control and Prevention (US)
- Simon Fraser University (CA)
- Brown University (US)
- National Center for Environmental Health (US)
- University of Cincinnati (US)
- University of Pennsylvania (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- International Journal of Hygiene and Environmental Health
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1016/j.ijheh.2026.114745
- Primary Topic
- Prenatal Substance Exposure Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00