Deciphering Teochew population’s genetic protective barrier: Apolipoprotein E- lipoprotein(a) kringle IV type 2 synergy as novel cardioprotective pathway

Xu <i>et al</i> provides crucial regional data for precision cardiovascular medicine in East Asia. This study focuses on the Teochew Han population in China for the first time and reveals the synergistic protective effect of the apolipoprotein E ε2 allele and high copy numbers of kringle IV type 2. This discovery holds significant importance for optimizing regional risk assessment models.