A Case-Based Review of Advanced Surgical Techniques in the Treatment of Incidentally Diagnosed Fibrolamellar Hepatocellular Carcinoma

Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare liver tumor that typically affects young adults without underlying liver disease. This case describes an incidental diagnosis of FL-HCC in a healthy 25-year-old male who presented to the Emergency Department with left flank pain. Imaging revealed a ureteropelvic junction stone with moderate hydronephrosis, as well as an unexpectedly large right hepatic mass. Further evaluation confirmed the diagnosis of FL-HCC. The patient underwent a successful right hepatectomy utilizing the anterior approach with hanging maneuver and extra-Glissonian right pedicle control. Postoperatively, the patient experienced an uneventful recovery. This case highlights the importance of thorough evaluation of incidental findings, even in asymptomatic and healthy individuals, and demonstrates the advantages of advanced surgical techniques in managing large liver tumors.

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Publication Details

Journal
Cureus
Published
2026-01-15
DOI
https://doi.org/10.7759/cureus.101612
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

A Case-Based Review of Advanced Surgical Techniques in the Treatment of Incidentally Diagnosed Fibrolamellar Hepatocellular Carcinoma

Mohamed Elfedaly, Ahmed Elfadaly, Basem Soliman, Omar Barakat et al.
Cureus
Hepatocellular Carcinoma Treatment and Prognosis
article

A Case-Based Review of Advanced Surgical Techniques in the Treatment of Incidentally Diagnosed Fibrolamellar Hepatocellular Carcinoma

Mohamed Elfedaly, Ahmed Elfadaly, Basem Soliman, Omar Barakat, Truman Archer
article en

Abstract

Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare liver tumor that typically affects young adults without underlying liver disease. This case describes an incidental diagnosis of FL-HCC in a healthy 25-year-old male who presented to the Emergency Department with left flank pain. Imaging revealed a ureteropelvic junction stone with moderate hydronephrosis, as well as an unexpectedly large right hepatic mass. Further evaluation confirmed the diagnosis of FL-HCC. The patient underwent a successful right hepatectomy utilizing the anterior approach with hanging maneuver and extra-Glissonian right pedicle control. Postoperatively, the patient experienced an uneventful recovery. This case highlights the importance of thorough evaluation of incidental findings, even in asymptomatic and healthy individuals, and demonstrates the advantages of advanced surgical techniques in managing large liver tumors.

CureusVol. 18(1)
Texas Tech University (US), San Joaquin General Hospital (US), Texas Tech University Health Sciences Center (US)
Good health and well-being
Openalex Percentile: Top 86%
Hepatocellular Carcinoma Treatment and Prognosis
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A Case-Based Review of Advanced Surgical Techniques in the Treatment of Incidentally Diagnosed Fibrolamellar Hepatocellular Carcinoma — Mohamed Elfedaly, Ahmed Elfadaly, et al. · Cureus (2026) | TGRS Research Map | TGRS