Clinical and Echocardiographic Characteristics Associated with Hypertension in a Cohort of People Living with and without HIV

In this HIV-prevalent cohort, hypertension was independently associated with left ventricular structural remodeling and advancing age, but not with circulating RAAS components or HIV status. These findings underscore the importance of echocardiographic assessment in hypertension evaluation and suggest that non-RAAS pathways may contribute to hypertensive cardiac remodeling in this setting.

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Journal
medRxiv
Published
2026-01-15
DOI
https://doi.org/10.64898/2026.01.12.26343986
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinical and Echocardiographic Characteristics Associated with Hypertension in a Cohort of People Living with and without HIV

Sepiso K. Masenga, Benson M. Hamooya, David Chisompola, Emmanuel Luwaya et al.
medRxiv
HIV-related health complications and treatments
article

Clinical and Echocardiographic Characteristics Associated with Hypertension in a Cohort of People Living with and without HIV

Sepiso K. Masenga, Benson M. Hamooya, David Chisompola, Emmanuel Luwaya, Sydney Mulamfu, Phinnoty Mwansa, Joreen P. Povia, Martin Chakulya
article en

Abstract

In this HIV-prevalent cohort, hypertension was independently associated with left ventricular structural remodeling and advancing age, but not with circulating RAAS components or HIV status. These findings underscore the importance of echocardiographic assessment in hypertension evaluation and suggest that non-RAAS pathways may contribute to hypertensive cardiac remodeling in this setting.

medRxiv
Livingstone Hospital (ZA), Mulungushi University (ZM)
American Heart Association, National Institutes of Health, Fogarty International Center, National Institute of Diabetes and Digestive and Kidney Diseases
Good health and well-being
Openalex Percentile: Top 89%
HIV-related health complications and treatments
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Clinical and Echocardiographic Characteristics Associated with Hypertension in a Cohort of People Living with and without HIV — Sepiso K. Masenga, Benson M. Hamooya, et al. · medRxiv (2026) | TGRS Research Map | TGRS