Liquiritigenin-loaded poly (acrylic acid)-carboxymethyl cellulose hydrogels: formulation optimization, performance evaluation, and assessment of therapeutic efficacy for wound healing and sepsis caused by wound bacterial infection

These findings demonstrate that the LQ-loaded hydrogel possesses excellent mechanical, biocompatible, and anti-inflammatory properties. Its dual-action as a pro-healing and antibacterial agent suggests it is a promising candidate for topical wound management and the prevention of infection-induced sepsis.