Structural and functional coupling alterations in autism spectrum disorder with and without comorbid attention deficit hyperactivity disorder
Our findings demonstrate both shared and subtype-specific alterations in SC-FC coupling in ASD. Comparing ASD subgroups clarifies that comorbid ADHD is associated with unique neural pathways, particularly involving cerebellar integration for attentional processes. Measuring SC-FC coupling offers a valuable approach for disentangling the heterogeneity in ASD and may aid in developing targeted interventions.
Authors
- Jingwen Yan
- Luming Hu (ORCID: https://orcid.org/0000-0003-3604-4905)
- Xuntao Yin (ORCID: https://orcid.org/0000-0002-8228-6908)
- Yan Zhou
Institutions
- Beijing Normal University (CN)
- Shantou University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- Guangdong Institute of Intelligent Manufacturing (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2026-01-15
- DOI
- https://doi.org/10.3389/fpsyt.2025.1704170
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Science and Technology of the People's Republic of China
- Guangzhou Municipal Science and Technology Project