Sex and Age Differences in Transcription Factor and Hormonal Immunostaining in Patients With Nonfunctioning Pituitary Adenomas
This study demonstrates that sex and age are important demographic factors associated with immunostaining patterns and TF lineage subtypes for NFPAs. Underlying endocrine factors dictated by age and sex may represent a role in tumorigenesis or progression of NFPAs.
Authors
- John D. Carmichael (ORCID: https://orcid.org/0000-0002-3194-9249)
- Mark S. Shiroishi (ORCID: https://orcid.org/0000-0002-1422-0288)
- David J. Coté (ORCID: https://orcid.org/0000-0001-5419-1517)
- William J. Zeng (ORCID: https://orcid.org/0000-0002-0415-1397)
- Apurva Prasad
- Robert G. Briggs (ORCID: https://orcid.org/0000-0001-9329-4471)
- Jonathan Sisti (ORCID: https://orcid.org/0000-0001-9011-1668)
- Gabriel Zada
- Racheal Peterson
- Kyle Hurth
- Ishan Shah
- Amara Emeh
- Erica Gillespie
Institutions
- University of Southern California (US)
- Neurological Surgery (US)
Publication Details
- Journal
- Operative Neurosurgery
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1227/ons.0000000000001903
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00