The role of changes in lactate dehydrogenase (LDH) levels in predicting COVID-19 severity and mortality: A biomarker analysis
ΔLDH is a powerful, independent predictor of COVID-19 severity, revealing a novel U-shaped risk pattern. The 181.5 U/L threshold offers clinically actionable guidance for risk stratification. These findings support the incorporation of serial LDH monitoring into COVID-19 management protocols.
Authors
- Ali Bahrami Far
- Behzad Einollahi (ORCID: https://orcid.org/0000-0002-0642-6278)
- Shahla Afsharpeyman
- Kiavash Hushmandi
- Seyed Hassan Saadat
- Fahime Shahjooie
- Hadi Norouzi
- Mohammad Farjami
Institutions
- Baqiyatallah University of Medical Sciences (IR)
- Semnan University of Medical Sciences (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Journal of Infection and Public Health
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1016/j.jiph.2026.103153
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00