Expression of low molecular weight protein tyrosine phosphatase in gastric cancer and its association with clinical outcomes and oncogenic hallmarks
LMWPTP is consistently upregulated in gastric and colorectal cancers and exhibits tumor-type-specific functional and immune associated features. These findings highlight its distinct oncogenic role and potential as a biomarker and therapeutic target in GC.
Authors
- Gwenny M. Fuhler (ORCID: https://orcid.org/0000-0001-9221-4855)
- Maikel Petrus Peppelenbosch (ORCID: https://orcid.org/0000-0001-9112-6028)
- Jun Yu (ORCID: https://orcid.org/0000-0002-5778-9343)
- Luochengling Xiang
- Ron Smits
- Ying Zhou
- Shanshan Li
Institutions
- Chinese University of Hong Kong (HK)
- Erasmus MC (NL)
- Chinese University of Hong Kong, Shenzhen (CN)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1186/s10020-025-01418-9
- Primary Topic
- Protein Tyrosine Phosphatases
- Type
- article
- Field-Weighted Citation Impact
- 0.00