Epicardial adipose tissue mediates the association between circulating hsa-miR-4750-3p and coronary artery disease in patients with type 2 diabetes mellitus
These findings suggest that the proposed miRNA-EAT regulatory axis may be involved in the pathogenesis of diabetic atherosclerosis, with EAT appearing to partially mediate the relationship between hsa-miR-4750-3p and CAD. The integrated approach linking EAT and miRNAs holds potential for CAD risk stratification in T2DM.
Authors
- Alicja Petniak (ORCID: https://orcid.org/0000-0001-9926-0870)
- Tomasz Zapolski (ORCID: https://orcid.org/0000-0001-9808-8853)
- Joanna Szydełko (ORCID: https://orcid.org/0000-0003-3744-9058)
- Marcin Czop (ORCID: https://orcid.org/0000-0002-8113-5841)
- Janusz Kocki (ORCID: https://orcid.org/0000-0002-9541-6353)
- Monika Lenart-Lipińska (ORCID: https://orcid.org/0000-0002-3418-6830)
- Beata Matyjaszek‐Matuszek (ORCID: https://orcid.org/0000-0001-7386-8087)
Institutions
- Medical University of Lublin (PL)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1186/s12933-025-03055-2
- Primary Topic
- Cardiovascular Disease and Adiposity
- Type
- article
- Field-Weighted Citation Impact
- 0.00