Brexpiprazole inhibits EMT and migration of colorectal cancer cells by downregulating the SREBP1/SNAI1 signaling pathway
Brexpiprazole inhibits the migration, invasion and metastasis of CRC cells by inhibiting the SREBP1/SNAI1 signalling pathway and downregulating the expression of EMT-related factors.
Authors
- Wei Chen (ORCID: https://orcid.org/0000-0001-6244-0595)
- Zhuoze Wu (ORCID: https://orcid.org/0009-0007-6851-3098)
- Wenjun Xia
- Lu Liu
- Ao Ma
- Xiaojie Liu
- Zhiyang Xia
- Jingyi He
Institutions
- North Sichuan Medical University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-15
- DOI
- https://doi.org/10.3389/fonc.2025.1734678
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 0.00