Research progress on the impact and mechanisms of helicobacter pylori infection on the efficacy of immunotherapy for gastric cancer

H. pylori has a complex influence on GC immunotherapy. Further research is needed to clarify the underlying mechanisms and assess the predictive value of H. pylori testing in clinical practice. Combining microbiome-based strategies with immunotherapy may enable more personalized and effective treatment.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-15
DOI
https://doi.org/10.3389/fonc.2025.1674814
Primary Topic
Helicobacter pylori-related gastroenterology studies
Type
article
Field-Weighted Citation Impact
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article

Research progress on the impact and mechanisms of helicobacter pylori infection on the efficacy of immunotherapy for gastric cancer

Weishuai Zhang, Chenyu Hou, Zicheng Bao, Bin Yao et al.
Frontiers in Oncology
Helicobacter pylori-related gastroenterology studies
article

Research progress on the impact and mechanisms of helicobacter pylori infection on the efficacy of immunotherapy for gastric cancer

Weishuai Zhang, Chenyu Hou, Zicheng Bao, Bin Yao, Yong Li
article en

Abstract

H. pylori has a complex influence on GC immunotherapy. Further research is needed to clarify the underlying mechanisms and assess the predictive value of H. pylori testing in clinical practice. Combining microbiome-based strategies with immunotherapy may enable more personalized and effective treatment.

Frontiers in OncologyVol. 15
Hebei Medical University (CN), Third Hospital of Hebei Medical University (CN), Fourth Hospital of Hebei Medical University (CN)
Openalex Percentile: Top 88%
Helicobacter pylori-related gastroenterology studies
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