Baseline morbidity and chronic medications as determinants of sepsis outcomes: focus on statins, corticosteroids, and NSAIDs in a population-based cohort of 59,578 patients

In this large population-based study, baseline comorbidities and chronic treatments significantly influenced sepsis outcomes. Statin use was associated with lower in-hospital mortality, whereas corticosteroids and NSAIDs were linked to worse prognosis. The GMA score proved useful in stratifying patient risk and may help to inform clinical decision-making and resource planning. ClinicalTrials.gov: NCT06354452.