Regulation of Aldosterone Secretion by Substance P and the Neurokinin Type 1 Receptor in Aldosterone‐Producing Adenomas
These findings suggest that the SP-NK1R signaling pathway may contribute to APA pathophysiology and represent a novel potential target for the pharmacological treatment of PA in a subset of patients.
Authors
- Jean‐Christophe Sabourin (ORCID: https://orcid.org/0000-0001-5490-066X)
- Maria‐Christina Zennaro (ORCID: https://orcid.org/0000-0001-5449-9191)
- Sylvie Renouf
- Céline Duparc (ORCID: https://orcid.org/0000-0002-7301-6287)
- H. Lefebvre
- L. Amar
- Estelle Louiset (ORCID: https://orcid.org/0000-0002-4723-095X)
- G. Defortescu
- Tchao Méatchi
- Margot D’Agostino
- Antoine‐Guy Lopez
- Gilles Manceau
- Gaël Nicolas
- Kelly De Sousa
- Fabio Luiz Fernandes‐Rosa
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Hôpital Européen Georges-Pompidou (FR)
- Normandie Université (FR)
- Hôpital Européen (FR)
- Paris Cardiovascular Research Center (FR)
- Centre Pompidou (FR)
- Centre Hospitalier Universitaire de Rouen (FR)
- Université de Rouen Normandie (FR)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1161/jaha.125.045539
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00