Risk Factors and an Interpretable Machine Learning Model for Predicting Spinal Epidural Lipomatosis

We developed and validated an interpretable prediction model that integrates clinical risk factors with an XGBoost algorithm and provides an actionable nomogram. This tool demonstrates strong potential to assist clinicians in early SEL detection and risk-stratified management, potentially enabling more targeted interventions for this underdiagnosed condition.

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Publication Details

Journal
Spine
Published
2026-01-12
DOI
https://doi.org/10.1097/brs.0000000000005614
Primary Topic
Spinal Hematomas and Complications
Type
article
Field-Weighted Citation Impact
0.00
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article

Risk Factors and an Interpretable Machine Learning Model for Predicting Spinal Epidural Lipomatosis

Yuan Tian, Wenbo Gu, Hua Zhang, Hui Ma et al.
Spine
Spinal Hematomas and Complications
article

Risk Factors and an Interpretable Machine Learning Model for Predicting Spinal Epidural Lipomatosis

Yuan Tian, Wenbo Gu, Hua Zhang, Hui Ma, Xi Zhu, Xiao Zhang, Haifeng Yuan, Donghui Cao, Yu Yang, Xiaoyong Chen, Hongyang Zhao, Xusheng Li
article en

Abstract

We developed and validated an interpretable prediction model that integrates clinical risk factors with an XGBoost algorithm and provides an actionable nomogram. This tool demonstrates strong potential to assist clinicians in early SEL detection and risk-stratified management, potentially enabling more targeted interventions for this underdiagnosed condition.

SpineVol. 51(8)
Qinghai University Affiliated Hospital (CN), Yinchuan First People's Hospital (CN), Jinchuan (China) (CN), Ningxia Hui Autonomous Region Peoples Hospital (CN), Ningxia Medical University (CN), Ningxia Medical University General Hospital (CN), Jingning County People's Hospital (CN), The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Peace, Justice and strong institutions
Openalex Percentile: Top 88%
Spinal Hematomas and Complications
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Risk Factors and an Interpretable Machine Learning Model for Predicting Spinal Epidural Lipomatosis — Yuan Tian, Wenbo Gu, et al. · Spine (2026) | TGRS Research Map | TGRS