A head-to-head comparison of TNF-α inhibitors as the first biologic treatment of rheumatoid arthritis

This hypothesis-generating study provides evidence that TNFis may not be equally effective. The uncertainty in the estimates highlights the need for a pragmatic randomized controlled trial to validate the findings. With decreasing costs of TNFis, such studies are increasingly feasible and critical to guide clinical decision-making.

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Publication Details

Journal
Lara D. Veeken
Published
2026-01-14
DOI
https://doi.org/10.1093/rheumatology/keag007
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
Field-Weighted Citation Impact
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article

A head-to-head comparison of TNF-α inhibitors as the first biologic treatment of rheumatoid arthritis

K. M. Fagerli, Eirik Klami Kristianslund, Inge Christoffer Olsen, Sella Aarrestad Provan et al.
Lara D. Veeken
Rheumatoid Arthritis Research and Therapies
article

A head-to-head comparison of TNF-α inhibitors as the first biologic treatment of rheumatoid arthritis

K. M. Fagerli, Eirik Klami Kristianslund, Inge Christoffer Olsen, Sella Aarrestad Provan, Amir Aamodt Kazemi, Joseph Sexton
article en

Abstract

This hypothesis-generating study provides evidence that TNFis may not be equally effective. The uncertainty in the estimates highlights the need for a pragmatic randomized controlled trial to validate the findings. With decreasing costs of TNFis, such studies are increasingly feasible and critical to guide clinical decision-making.

Lara D. VeekenVol. 65(2)
Oslo University Hospital (NO), University of Oslo (NO), Diakonhjemmet Hospital (NO)
Good health and well-being
Openalex Percentile: Top 89%
Rheumatoid Arthritis Research and Therapies
DOIOpen Access PDFOpenAlex
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A head-to-head comparison of TNF-α inhibitors as the first biologic treatment of rheumatoid arthritis — K. M. Fagerli, Eirik Klami Kristianslund, et al. · Lara D. Veeken (2026) | TGRS Research Map | TGRS