Regulating the Impact of Hypertension on Stroke: Therapeutic Potential of a Peptide Mimetic of Tyrosine Phosphatase STEP
The efficacy of the novel STEP-peptide in mitigating brain damage and improving functional recovery in a preclinical stroke model of hypertension holds promise for the development of potential strategies to treat acute ischemic stroke in the population with hypertension.
Authors
- Prabu Paramasivam (ORCID: https://orcid.org/0000-0002-8626-1601)
- Sathyanarayanan Rajagopal (ORCID: https://orcid.org/0000-0003-1054-3730)
- Seong Won Choi
- Surojit Paul
- Ranjana Poddar (ORCID: https://orcid.org/0000-0002-8459-5560)
Institutions
- University of New Mexico (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1161/jaha.125.042669
- Primary Topic
- Protein Tyrosine Phosphatases
- Type
- article
- Field-Weighted Citation Impact
- 0.00