Neurocognitive risk markers in first-episode major depressive disorder with positive family history: a large-scale case–control study
Language dysfunction and global cognitive impairment may be independent markers of first-episode MDD with PFH. Early cognitive profiling may facilitate targeted prevention in high-risk relatives.
Authors
- Jianjun Guan
- Wenmei Fang
- Min Pan (ORCID: https://orcid.org/0009-0006-7544-4492)
- Boyu Zhang (ORCID: https://orcid.org/0000-0003-1339-2173)
- Xialong Cheng
- Xulai Zhang
- Zhiyong Li
Institutions
- Anhui Medical University (CN)
- The Fourth People's Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- Anhui Mental Health Center (CN)
- Fourth Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fpsyt.2025.1662007
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00