Association and predictive value of blood branched-chain and excitatory amino acids with autism spectrum disorder severity
Blood BCAAs and EAAs were closely associated with ASD severity, with leucine/isoleucine as the strongest predictor. Amino acid profile-based models provide biomarker evidence for identifying severe ASD and precision intervention.
Authors
- Gang Feng (ORCID: https://orcid.org/0000-0002-4269-6208)
- Xiaofeng Mei
- Y S Wang
- Xueping Yang (ORCID: https://orcid.org/0000-0002-9184-8116)
- Jing Li (ORCID: https://orcid.org/0000-0002-4289-4829)
- Ying Ding (ORCID: https://orcid.org/0000-0002-0172-1091)
- Rongyi Zhou
- Q. Zhang
- Weili Dang
- Liangliang Bi
- Xia Zhang
Institutions
- Henan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Henan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1186/s12887-025-06501-y
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00