Molecular features of early- vs. late-onset gastric cancer: a systematic review and meta-analysis
EOGC represents a biologically distinct subset of gastric cancer with unique genomic and immunological features. These findings support age-specific diagnostic approaches and emphasize the value of multiomic strategies to uncover the mechanisms driving early-onset disease.
Authors
- Wenhan Shi
- Zihan Zhou (ORCID: https://orcid.org/0000-0002-0285-702X)
- Qiuyuan Yao
- Xinmei Lin (ORCID: https://orcid.org/0009-0001-8011-1944)
- Degang Li
- Yu Sun
Institutions
- Sun Yat-sen University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1186/s12885-026-15567-5
- Citations
- 1
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 36.44