Gut microbiota composition correlates with insomnia severity: insights from high-throughput sequencing analysis

Gut microbiota structure is intrinsically linked to insomnia severity, characterized by a diminished F/B ratio, reduced <i>Clostridia</i> abundance, and enrichment of pro-inflammatory taxa. The reduction in SCFA-producing <i>Clostridia</i> may impair neuro-immune regulation via the gut-brain axis, potentially exacerbating sleep dysregulation.