FOXM1 regulates platelet-induced anoikis resistance in pancreatic cancer cells

Overall, these findings suggest that targeting FOXM1 may be a promising therapeutic strategy to interfere with the metastatic progression of pancreatic cancer, which might particularly benefit patients with high blood platelet counts.

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Publication Details

Journal
Cell Communication and Signaling
Published
2026-01-14
DOI
https://doi.org/10.1186/s12964-025-02644-8
Primary Topic
FOXO transcription factor regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

FOXM1 regulates platelet-induced anoikis resistance in pancreatic cancer cells

Helmut Laumen, Beate Heydel, Carolin T. Neu, Monika Haemmerle et al.
Cell Communication and Signaling
FOXO transcription factor regulation
article

FOXM1 regulates platelet-induced anoikis resistance in pancreatic cancer cells

Helmut Laumen, Beate Heydel, Carolin T. Neu, Monika Haemmerle, Tony Gutschner, Ferdinand Krannich, Alissa Ernesti-Soldatkin
article en

Abstract

Overall, these findings suggest that targeting FOXM1 may be a promising therapeutic strategy to interfere with the metastatic progression of pancreatic cancer, which might particularly benefit patients with high blood platelet counts.

Cell Communication and SignalingVol. 24(1)
Martin Luther University Halle-Wittenberg (DE), Ludwig-Maximilians-Universität München (DE)
Good health and well-being
Openalex Percentile: Top 88%
FOXO transcription factor regulation
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