Associations of Serum Complement Biomarkers With Adverse Clinical Outcomes Among Patients With Ischemic Stroke

High serum complement C3 and C4 levels were associated with increased risks of adverse outcomes at discharge after ischemic stroke, suggesting that the complement system might be implicated in the progression of ischemic stroke and could be potential intervention targets for improving prognosis.

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Publication Details

Journal
Journal of the American Heart Association
Published
2026-01-14
DOI
https://doi.org/10.1161/jaha.125.046136
Primary Topic
Complement system in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Associations of Serum Complement Biomarkers With Adverse Clinical Outcomes Among Patients With Ischemic Stroke

Daoxia Guo, Y. Lynn Wang, Lulu Sun, Huicong Niu et al.
Journal of the American Heart Association
Complement system in diseases
article

Associations of Serum Complement Biomarkers With Adverse Clinical Outcomes Among Patients With Ischemic Stroke

Daoxia Guo, Y. Lynn Wang, Lulu Sun, Huicong Niu, Min Chu, Yang Liu, Xuechun Wu, Jing Zhao
article en

Abstract

High serum complement C3 and C4 levels were associated with increased risks of adverse outcomes at discharge after ischemic stroke, suggesting that the complement system might be implicated in the progression of ischemic stroke and could be potential intervention targets for improving prognosis.

Journal of the American Heart AssociationVol. 15(2)
Shanghai Jiao Tong University (CN), Fudan University (CN), Soochow University (CN)
Openalex Percentile: Top 88%
Complement system in diseases
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