Impact of folic acid supplementation on seizures, maternal and fetal outcomes in pregnant Chinese women with epilepsy
Periconceptional FA intake by women with epilepsy was associated with an approximately 66% decreased risk of abortion and improved seizure control during pregnancy. Low-dose FA may be insufficient to prevent adverse maternal-fetal outcomes in this population. Further studies are warranted to confirm these findings.
Authors
- Terence John O'Brien (ORCID: https://orcid.org/0000-0002-7198-8621)
- Ammar Taha Abdullah Abdulaziz (ORCID: https://orcid.org/0000-0003-3333-4800)
- Y. M. Chen
- Jie Liu (ORCID: https://orcid.org/0000-0001-8883-5712)
- Xin Wu (ORCID: https://orcid.org/0000-0002-1954-1005)
- Jinmei Li
- Xiaoting Hao
- Tao Li
- Lu Lu
- Josemir W. Sander
- Nanya Hao
- Xu Lin
- Lei Chen
- Dong Zhou
Institutions
- The Royal Melbourne Hospital (AU)
- University of Electronic Science and Technology of China (CN)
- Sichuan University (CN)
- The Alfred Hospital (AU)
- Epilepsy Research UK (GB)
- West China Second University Hospital of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Monash Alfred Psychiatry Research centre (AU)
- University College London (GB)
- Epilepsy Society (GB)
- Monash University (AU)
Publication Details
- Journal
- Epilepsia
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1002/epi.70093
- Primary Topic
- Pharmacological Effects and Toxicity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00