Cancellation of the vestibulo-ocular reflex during smooth pursuit in patients with maculopathy
We confirmed that VOR responses to actively generated head movements were similarly intact in both groups. Our analyses of the pursuit data indicate that, regardless of visual function older adults attenuate eye-driven pursuit when the head is unrestrained (as compared to the restrained condition), and those with CFL fail to exploit residual VOR cancellation, helping to explain their persistent gaze-tracking deficits.
Authors
- Anca Velisar (ORCID: https://orcid.org/0000-0002-8349-7782)
- Natela Shanidze (ORCID: https://orcid.org/0000-0003-2143-8848)
Institutions
- Smith-Kettlewell Eye Research Institute (US)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fneur.2025.1632527
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute on Disability, Independent Living, and Rehabilitation Research