Impact of gender and chelation on the ferritin–liver function test relationship in transfusion-dependent β-thalassaemia
Gender and the chelation regimen modify the ferritin-LFT relationship in TDT. AST is a consistent predictor of ferritin across all groups, while bilirubin and interaction terms contribute in specific subgroups. These findings highlight the need for gender- and regimen-specific interpretation of biochemical markers, especially where advanced iron assessment is unavailable.
Authors
- Radhwan M. Hussein (ORCID: https://orcid.org/0000-0002-2318-8689)
- H. Muhammad (ORCID: https://orcid.org/0009-0005-2356-3185)
- Hamid Alghurabi (ORCID: https://orcid.org/0009-0003-0075-1277)
- Muntadher Zmezim
- Zahraa Alaa Alrufaei
- Zahraa Sabbar Omran
- Mohammed Qasim Rasheed
- Mustafa Ridha Shihan
Institutions
- Baghdad Medical City (IQ)
- Ahl Al Bayt University (IQ)
- Ministry of Health (IQ)
- University of Kerbala (IQ)
Publication Details
- Journal
- European Journal of Hospital Pharmacy
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1136/ejhpharm-2025-004730
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00