Prevalence, characteristics, and plasmid dynamics of mcr-1 positive Enterobacteriaceae in Hainan, China: a preliminary genomic investigation

This preliminary study indicates a low prevalence of <i>mcr-1</i> in our setting. However, the genomic identification of conjugative plasmids, including one carrying both <i>mcr-1</i> and an extended-spectrum β-lactamase gene, highlights a tangible risk for horizontal co-transfer of resistance. The association of these isolates with healthcare exposures underscores the need for ongoing surveillance to monitor plasmid evolution in hospital ecosystems.