Jujuboside A induces bladder cancer cell apoptosis by inhibiting ATP1A2-mediated mitochondrial energy metabolism regulation
This study elucidated the molecular mechanism by which JuA regulates mitochondrial energy metabolism and induces apoptosis in bladder cancer cells through targeted inhibition of ATP1A2. These findings reveal the crucial role of ATP1A2 in the energy metabolism and survival of bladder cancer cells, providing a new molecular perspective for a deeper understanding of the pathological mechanisms of bladder cancer.
Authors
- Mengqing Zhu (ORCID: https://orcid.org/0000-0001-9422-6550)
- Lixin Ren
- Yaxuan Wang (ORCID: https://orcid.org/0009-0003-9662-1871)
- Yumin Jia
- Yuepeng Liu
- Shuhui An
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Cancer Biology & Therapy
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1080/15384047.2026.2615418
- Primary Topic
- Ziziphus Jujuba Studies and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00