Intravascular lithotripsy versus rotational atherectomy in calcified coronary artery disease: a systematic review and meta-analysis

IVL and rotational atherectomy are excellent options to be utilized in the plaque modification of calcified coronary artery lesions before drug-eluting stents implantation with comparable clinical safety and efficacy outcomes. Rotational atherectomy and IVL yielded comparable clinical outcomes for MACE. IVL was associated with higher procedural success, fewer periprocedural complications (perforation, slow flow/no‑reflow), and shorter procedures. However, the higher costs incurred by IVL represent a major drawback that limits the use and the standardization of such a technique in clinical practice.

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Publication Details

Journal
Coronary Artery Disease
Published
2026-01-13
DOI
https://doi.org/10.1097/mca.0000000000001611
Primary Topic
Coronary Interventions and Diagnostics
Type
article
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article

Intravascular lithotripsy versus rotational atherectomy in calcified coronary artery disease: a systematic review and meta-analysis

AlMothana Manasrah, Moumen Arnaout, Walaa Shehada, Mohammad Tanashat et al.
Coronary Artery Disease
Coronary Interventions and Diagnostics
article

Intravascular lithotripsy versus rotational atherectomy in calcified coronary artery disease: a systematic review and meta-analysis

AlMothana Manasrah, Moumen Arnaout, Walaa Shehada, Mohammad Tanashat, Basel F. Alqeeq, Basma Badrawy Khalefa, Shahd Alqato, Abdelrahman M. Elettreby, Ahmad Jabri, Malik Allahham, Bassel Gaballah, Alshayma Alalawneh, Naif Fawaz Aljamlan, Pedro Villablanca
article en

Abstract

IVL and rotational atherectomy are excellent options to be utilized in the plaque modification of calcified coronary artery lesions before drug-eluting stents implantation with comparable clinical safety and efficacy outcomes. Rotational atherectomy and IVL yielded comparable clinical outcomes for MACE. IVL was associated with higher procedural success, fewer periprocedural complications (perforation, slow flow/no‑reflow), and shorter procedures. However, the higher costs incurred by IVL represent a major drawback that limits the use and the standardization of such a technique in clinical practice.

Coronary Artery Disease
University of Aleppo (SY), Ain Shams University (EG), Amman Arab University (JO), Jordan University of Science and Technology (JO), Mansoura University (EG), Islamic University of Gaza (PS), King Saud University (SA), Henry Ford Hospital (US), United Health Services (US), National Heart Institute (EG), MetroHealth Medical Center (US), Case Western Reserve University (US), Yarmouk University (JO), Michigan State University (US)
Good health and well-being
Openalex Percentile: Top 88%
Coronary Interventions and Diagnostics
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