Lack of striatal-enriched protein tyrosine phosphatase affected the serotonin system, behavior, and brain morphology in mice

The data obtained in this study indicate a significant role of STEP in the regulation of behavior and brain architecture, and highlight the connection between STEP and the 5-HT system.

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Journal
Frontiers in Psychiatry
Published
2026-01-14
DOI
https://doi.org/10.3389/fpsyt.2025.1730197
Primary Topic
Protein Tyrosine Phosphatases
Type
article
Field-Weighted Citation Impact
0.00

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article

Lack of striatal-enriched protein tyrosine phosphatase affected the serotonin system, behavior, and brain morphology in mice

Д. В. Базовкина, О. Б. Шевелев, Nariman Battulin, Н. В. Хоцкин et al.
Frontiers in Psychiatry
Protein Tyrosine Phosphatases
article

Lack of striatal-enriched protein tyrosine phosphatase affected the serotonin system, behavior, and brain morphology in mice

Д. В. Базовкина, О. Б. Шевелев, Nariman Battulin, Н. В. Хоцкин, А. B. Arefieva, Vitalii S. Moskaliuk, I. A. Serova, Alexey Korablev, Polina D. Komleva, Elizabeth S. Kulikova, Alexander Kulikov, Vladimir Naumenko
article en

Abstract

The data obtained in this study indicate a significant role of STEP in the regulation of behavior and brain architecture, and highlight the connection between STEP and the 5-HT system.

Frontiers in PsychiatryVol. 16
National Research Tomsk State University (RU), State Research Center of Virology and Biotechnology VECTOR (RU), Tomsk Polytechnic University (RU), Institute of Cytology and Genetics (RU), Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (RU)
Siberian Branch, Russian Academy of Sciences, Russian Science Foundation
Openalex Percentile: Top 88%
Protein Tyrosine Phosphatases
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Lack of striatal-enriched protein tyrosine phosphatase affected the serotonin system, behavior, and brain morphology in mice — Д. В. Базовкина, О. Б. Шевелев, et al. · Frontiers in Psychiatry (2026) | TGRS Research Map | TGRS