Müllerian adenosarcoma mimicking cervical carcinoma in a 79-year-old woman: diagnostic challenges and laparoscopictreatment: a case report

Uterine Müllerian adenosarcoma rarely presents as a cervical "cancer-like" mass; we report the first detailed case in a 79-year-old woman whose 5-cm exophytic lesion mimicked advanced cervical carcinoma on imaging. She presented with 2 weeks of post-menopausal bleeding and a friable polyp protruding through the cervical os; MRI described a bulky cervical tumour extending into the lower uterine segment, while tumour markers remained normal. Initial biopsy was inconclusive; subsequent excision and hysterectomy revealed FIGO stage Ib1 low-grade adenosarcoma originating from the lower uterine segment with superficial cervical involvement. Laparoscopic total hysterectomy with bilateral salpingo-oophorectomy was performed uneventfully, and at 7 months she remains disease-free. The case underlines that adenosarcoma can masquerade as cervical cancer, emphasises the need for generous tissue sampling and WT1/ER-based immunohistochemistry to define tumour origin, and confirms excellent outcomes with complete surgical excision for stage I disease.

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Publication Details

Journal
Pan African Medical Journal
Published
2025-11-13
DOI
https://doi.org/10.11604/pamj.2025.52.110.49172
Primary Topic
Uterine Myomas and Treatments
Type
article
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article

Müllerian adenosarcoma mimicking cervical carcinoma in a 79-year-old woman: diagnostic challenges and laparoscopictreatment: a case report

Jia Bian, Y. C. Lan, Jie Hu, Fang Zhang
Pan African Medical Journal
Uterine Myomas and Treatments
article

Müllerian adenosarcoma mimicking cervical carcinoma in a 79-year-old woman: diagnostic challenges and laparoscopictreatment: a case report

Jia Bian, Y. C. Lan, Jie Hu, Fang Zhang
article en

Abstract

Uterine Müllerian adenosarcoma rarely presents as a cervical "cancer-like" mass; we report the first detailed case in a 79-year-old woman whose 5-cm exophytic lesion mimicked advanced cervical carcinoma on imaging. She presented with 2 weeks of post-menopausal bleeding and a friable polyp protruding through the cervical os; MRI described a bulky cervical tumour extending into the lower uterine segment, while tumour markers remained normal. Initial biopsy was inconclusive; subsequent excision and hysterectomy revealed FIGO stage Ib1 low-grade adenosarcoma originating from the lower uterine segment with superficial cervical involvement. Laparoscopic total hysterectomy with bilateral salpingo-oophorectomy was performed uneventfully, and at 7 months she remains disease-free. The case underlines that adenosarcoma can masquerade as cervical cancer, emphasises the need for generous tissue sampling and WT1/ER-based immunohistochemistry to define tumour origin, and confirms excellent outcomes with complete surgical excision for stage I disease.

Pan African Medical JournalVol. 52
Ningbo University Affiliated Hospital (CN)
Good health and well-being
Openalex Percentile: Top 23%
Uterine Myomas and Treatments
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Müllerian adenosarcoma mimicking cervical carcinoma in a 79-year-old woman: diagnostic challenges and laparoscopictreatment: a case report — Jia Bian, Y. C. Lan, et al. · Pan African Medical Journal (2025) | TGRS Research Map | TGRS