Skin sympathetic nerve activity and nocturnal septal ST-segment elevation
Hyperadrenergic postural orthostatic tachycardia syndrome (hPOTS) is a subgroup of POTS with prominent sympathetic activation symptoms. We recently recorded skin sympathetic nerve activity (SKNA) in ambulatory participants with hPOTS at baseline and after being treated with clonidine.1 We performed a secondary analysis to determine if reduced average SKNA (aSKNA) during sleep was associated with ST elevation.
Authors
- Anxhela Kote
- Noel Bairey Merz
- Xiao Liu
- Sthira Rao
- Xiaochun Li
- Peng-Sheng Chen
Institutions
- Cedars-Sinai Medical Center (US)
- Cedars-Sinai Smidt Heart Institute (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Heart Rhythm O2
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1016/j.hroo.2026.01.009
- Primary Topic
- Cardiovascular Syncope and Autonomic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Heart Association
- Cedars-Sinai Medical Center