Bilateral Blindness in a Patient With Vestibular Schwannoma and Empty Sella Syndrome: A Case Report

We report a rare clinical presentation of a T4b vestibular schwannoma causing severe compression of the brainstem and fourth ventricle, associated with obstructive hydrocephalus and empty sella syndrome, in a patient presenting with profound neurological and ophthalmological deficits, most notably complete bilateral blindness. Radical microsurgical resection was achieved via a lateral suboccipital (retromastoid) approach, resulting in gross-total tumor removal with preservation of most cranial nerves. Postoperatively, the patient developed House-Brackmann grade III facial palsy. Hydrocephalus resolved without the need for cerebrospinal fluid diversion, gait instability improved, and visual deficits persisted. This case highlights the exceptional association of vestibular schwannoma with bilateral blindness and empty sella syndrome, emphasizing the importance of early recognition and timely surgical intervention in advanced tumors to minimize morbidity and optimize outcomes.

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Publication Details

Journal
Cureus
Published
2026-01-14
DOI
https://doi.org/10.7759/cureus.101505
Primary Topic
Meningioma and schwannoma management
Type
article
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article

Bilateral Blindness in a Patient With Vestibular Schwannoma and Empty Sella Syndrome: A Case Report

Thamer Hamad Alsharif, Kemal Dizdarević, Ammar M Bahati, Mashhour A Alsuwat
Cureus
Meningioma and schwannoma management
article

Bilateral Blindness in a Patient With Vestibular Schwannoma and Empty Sella Syndrome: A Case Report

Thamer Hamad Alsharif, Kemal Dizdarević, Ammar M Bahati, Mashhour A Alsuwat
article en

Abstract

We report a rare clinical presentation of a T4b vestibular schwannoma causing severe compression of the brainstem and fourth ventricle, associated with obstructive hydrocephalus and empty sella syndrome, in a patient presenting with profound neurological and ophthalmological deficits, most notably complete bilateral blindness. Radical microsurgical resection was achieved via a lateral suboccipital (retromastoid) approach, resulting in gross-total tumor removal with preservation of most cranial nerves. Postoperatively, the patient developed House-Brackmann grade III facial palsy. Hydrocephalus resolved without the need for cerebrospinal fluid diversion, gait instability improved, and visual deficits persisted. This case highlights the exceptional association of vestibular schwannoma with bilateral blindness and empty sella syndrome, emphasizing the importance of early recognition and timely surgical intervention in advanced tumors to minimize morbidity and optimize outcomes.

CureusVol. 18(1)
Royal College of Surgeons in Ireland (IE), King Abdulaziz Hospital (SA), King Fahad Hospital Jeddah (SA)
Good health and well-being
Openalex Percentile: Top 88%
Meningioma and schwannoma management
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Bilateral Blindness in a Patient With Vestibular Schwannoma and Empty Sella Syndrome: A Case Report — Thamer Hamad Alsharif, Kemal Dizdarević, et al. · Cureus (2026) | TGRS Research Map | TGRS