Association of IFN-γ and IFN-γ Receptor-1 Genes Polymorphisms with Hepatitis C Virus Infection Chronicity and Severity in Pakistani Patients
The current study shows that the AA genotype of the IFN-γ and TC genotype of the IFN-γR1 genes are associated with increased susceptibility and HCV chronicity. While the TT genotype of the IFN-γ and the CC genotype of the IFN-γR1 may confer a protective effect.
Authors
- Majid Khan (ORCID: https://orcid.org/0000-0002-9287-2046)
- Muhammad M. Yaqoob (ORCID: https://orcid.org/0000-0002-9904-127X)
- Sanaullah Khan (ORCID: https://orcid.org/0000-0003-3164-3036)
- Muhammad Adnan (ORCID: https://orcid.org/0000-0002-7424-4740)
- Muhammad Bar Khan (ORCID: https://orcid.org/0000-0003-0747-1027)
- Khair Rafiq
Institutions
- University of Insubria (IT)
- Khyber Medical University (PK)
- University of Peshawar (PK)
Publication Details
- Journal
- Viral Immunology
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1177/08828245251415180
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00