Independent external validation of the LIFE-HF clinical prediction model using the GUIDE-IT trial
In a contemporary, high-risk North American HF with reduced ejection fraction cohort, the LIFE-HF models showed good discrimination but systematically underpredicted 1-year risk. The mortality model may support risk-informed decision-making, whereas the composite model requires further validation.
Authors
- Mohsen Sadatsafavi (ORCID: https://orcid.org/0000-0002-0419-7862)
- Nathaniel M. Hawkins (ORCID: https://orcid.org/0000-0003-1286-2014)
- Douglas S Lee
- Ricky D Turgeon
Institutions
- University of British Columbia (CA)
- Centre for Advancing Health Outcomes (CA)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1093/eschf/xvag007
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00