A new chromone from the roots of <i>Stellera chamaejasme</i> L.

A new chromone (<b>1</b>), together with three known compounds (<b>2-4</b>), was isolated from the roots of <i>Stellera chamaejasme</i> L. The structure of compound <b>1</b> was elucidated by comprehensive spectroscopic analyses, including 1D and 2D NMR (HSQC, COSY, HMBC) and HR-ESI-MS. The absolute configuration was further determined by comparison of the experimental and time-dependent density functional theory (TDDFT)-calculated electronic circular dichroism (ECD) spectra. And all compounds (<b>1-4</b>) exhibited weak cytotoxicity against HL-60 and HeLa cell lines.