Prognostic impact of TROP2 in adenocarcinoma of the esophageal junction and stomach
In Caucasian AEG/S patients, TROP2 is expressed in the majority of cases. TROP2 expression intensity itself has an impact on survival, which could be explained by a more aggressive phenotype, which leads to lymphatic invasion and lymph node metastasis.
Authors
- Ulrike Stein (ORCID: https://orcid.org/0000-0001-7006-282X)
- Anselm Pittrof
- Christoph Treese (ORCID: https://orcid.org/0000-0001-9120-6773)
- S Daum (ORCID: https://orcid.org/0000-0003-0060-6013)
- Alexander Arnold (ORCID: https://orcid.org/0000-0002-7727-0688)
- Jonas J. Staudacher (ORCID: https://orcid.org/0000-0001-5697-2798)
- Beate Rau
- Erika Gebel Berg
- David Horst
- Lisa Marie Eich
Institutions
- Max Delbrück Center (DE)
- Franklin University (US)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Clinical & Translational Oncology
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1007/s12094-025-04203-6
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00