Targeting NF-kappa B/proinflammatory cytokines/ TGF-β/ TIMP-1 pathway by crocin enhances recovery from hepatic fibrosis in rats

Crocin exerts a promising curative effect against CCl₄-induced hepatic fibrosis in rats by suppressing NF-κB driven inflammation and profibrogenic mediators, thereby limiting collagen deposition.

Authors

Institutions

Publication Details

Journal
Scientific Reports
Published
2026-01-14
DOI
https://doi.org/10.1038/s41598-025-32672-w
Primary Topic
Saffron Plant Research Studies
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Targeting NF-kappa B/proinflammatory cytokines/ TGF-β/ TIMP-1 pathway by crocin enhances recovery from hepatic fibrosis in rats

Raed S. Ismail, Samir A. Salama, Memy H. Hassan
Scientific Reports
Saffron Plant Research Studies
article

Targeting NF-kappa B/proinflammatory cytokines/ TGF-β/ TIMP-1 pathway by crocin enhances recovery from hepatic fibrosis in rats

Raed S. Ismail, Samir A. Salama, Memy H. Hassan
article en

Abstract

Crocin exerts a promising curative effect against CCl₄-induced hepatic fibrosis in rats by suppressing NF-κB driven inflammation and profibrogenic mediators, thereby limiting collagen deposition.

Scientific ReportsVol. 16(1)
Taif University (SA), Al-Azhar University (EG)
Science and Technology Development Fund
Openalex Percentile: Top 88%
Saffron Plant Research Studies
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.