Quantifying maternal antibody transfer to colostrum and cord blood reveals virus-specific selectivity in dogs
These findings provide the most comprehensive quantification to date of MatAb transfer routes in dogs, revealing preferential transfer of virus-specific IgG to colostrum and highlighting the crucial role of colostrum intake in neonatal immunity. This work establishes a foundation for identifying antibody characteristics that influence MatAb transfer efficiency and reinforces the importance of ensuring that dams have adequate titers of virus-specific IgG prior to breeding.
Authors
- Abigail M. Reid (ORCID: https://orcid.org/0000-0003-3441-217X)
- Soon Hon Cheong (ORCID: https://orcid.org/0000-0001-9002-7589)
- Sarah Caddy (ORCID: https://orcid.org/0000-0002-9790-7420)
- Sarah Woodyear (ORCID: https://orcid.org/0009-0006-5071-103X)
- Lotta Henni Truyen (ORCID: https://orcid.org/0009-0006-8454-3177)
- Serena S. Teh
- Ana Alice Pimeta-Pereira (ORCID: https://orcid.org/0009-0007-3599-8885)
- Jessica Palmeri (ORCID: https://orcid.org/0009-0000-9636-3364)
- Ella Lanman
- Tom M. Lonergan
- Alexis A. E. Peprah
Institutions
- University of Veterinary Medicine Hannover, Foundation (DE)
- Cornell University (US)
- Département Santé Animale (FR)
- University of Veterinary Medicine (HU)
- New York State College of Veterinary Medicine (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fimmu.2025.1753521
- Primary Topic
- Animal health and immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00