Menopausal Status Associated With Docetaxel-Induced Vascular Dysfunction in Breast Cancer Patients

TAC-induced vascular dysfunction seen in breast cancer survivors is absent in premenopausal women, likely owing to estrogen-mediated protection against oxidative stress and eNOS inhibition.

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Publication Details

Journal
Journal of the American College of Cardiology
Published
2026-01-14
DOI
https://doi.org/10.1016/j.jacc.2025.10.077
Citations
1
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
Field-Weighted Citation Impact
30.07
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article

Menopausal Status Associated With Docetaxel-Induced Vascular Dysfunction in Breast Cancer Patients

Piotr Szczepaniak, Iwona Laksa, Jakub Jurczyk, T. Grodzicki et al.
1 citations
Journal of the American College of Cardiology
Chemotherapy-induced cardiotoxicity and mitigation
30.07
article

Menopausal Status Associated With Docetaxel-Induced Vascular Dysfunction in Breast Cancer Patients

Piotr Szczepaniak, Iwona Laksa, Jakub Jurczyk, T. Grodzicki, Joanna Sulicka‐Grodzicka, Paulina Sajdak, Ryszard Nosalski, Karolina Brzuszkiewicz, Diana Hodorowicz‐Zaniewska, Ewelina Józefczuk, Tomasz J Guzik, Tomasz Mikolajczyk, Mateusz Gorski, Joanna Streb, Mateusz Siedlinski
article en
1 citations

Abstract

TAC-induced vascular dysfunction seen in breast cancer survivors is absent in premenopausal women, likely owing to estrogen-mediated protection against oxidative stress and eNOS inhibition.

Journal of the American College of CardiologyVol. 87(6)
Jagiellonian University (PL), Manchester Academic Health Science Centre (GB), The Queen's Medical Research Institute (GB), University of Edinburgh (GB)
Good health and well-being
Openalex Percentile: Top 2%
Chemotherapy-induced cardiotoxicity and mitigation
30.07
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